Study of the Retrotransposon-Derived Human PEG10 Protease
Paternally expressed gene 10 (PEG10) is a human retrotransposon-derived imprinted gene.Previous works have demonstrated that a mutation in the coding sequence of this gene is lethal with regard to embryological age due to defects of placental development.In addition, PEG10 is implicated in several malignancies, such as pancreatic cancer and hepatoc